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1

An Archaeosome-Adjuvanted Vaccine and Checkpoint Inhibitor Therapy Combination Significantly Enhances Protection from Murine Melanoma

Stark, Felicity, Weeratna, Risini, Deschatelets, Lise, Gurnani, Komal, Dudani, Renu, McCluskie, Michael, Krishnan, Lakshmi

Journal:

Year:

2017

Language:

english

File:

PDF, 1.45 MB

english, 2017

2

Sequence Motifs in Adenoviral DNA Block Immune Activation by Stimulatory CpG Motifs

Arthur M. Krieg, Tong Wu, Risini Weeratna, Susan M. Efler, Laurie Love-Homan, Lin Yang, Ae-Kyung Yi, Dan Short and Heather L. Davis

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 2.24 MB

english, 1998

3

Anti-IgE Qb-VLP Conjugate Vaccine Self-Adjuvants through Activation of TLR7

Akache, Bassel, Weeratna, Risini, Deora, Aparna, Thorn, Jennifer, Champion, Brian, Merson, James, Davis, Heather, McCluskie, Michael

Journal:

Year:

2016

Language:

english

File:

PDF, 983 KB

english, 2016

4

A Chemical Derivatization Strategy for Extending the Identification of MHC Class I Immunopeptides

Chen, Rui, Fauteux, Francois, Foote, Simon, Stupak, Jacek, Tremblay, Tammy-Lynn, Gurnani, Komal, Fulton, Kelly M., Weeratna, Risini, Twine, Susan M., Li, Jianjun

Journal:

Analytical Chemistry

Year:

2018

Language:

english

File:

PDF, 1.20 MB

english, 2018

5

CpG-mediated augmentation of CD8 + T-cell responses in mice is attenuated by a water-in-oil emulsion (Montanide ISA-51) but enhanced by an oil-in-water emulsion (IDRI SE)

Makinen, Shawn R., Zhu, Qin, Davis, Heather L., Weeratna, Risini D.

Journal:

International Immunology

Year:

2016

Language:

english

File:

PDF, 568 KB

english, 2016

6

Enhancement of Anti-Tumor Efficacy of Paclitaxel by CpG ODN; TLR9 Agonist in Metastatic Murine Cancer Models

Weeratna, Risini, Bourne, Liana, Sullivan, Shannon, Davis, Heather, Krieg, Arthur

Journal:

Journal of Immunotherapy

Year:

2004

Language:

english

File:

PDF, 63 KB

english, 2004

7

Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities

Jörg Vollmer, Risini Weeratna, Paul Payette, Marion Jurk, Christian Schetter, Meike Laucht, Tanja Wader, Sibylle Tluk, Ming Liu, Heather L. Davis, Arthur M. Krieg

Journal:

European Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 514 KB

english, 2004

8

Negative Regulation of the Type I Interferon Signaling Pathway by Synthetic Toll-Like Receptor 7 Ligands

Forsbach, Alexandra, Müller, Christian, Montino, Carmen, Kritzler, Andrea, Nguyen, Toan, Weeratna, Risini, Jurk, Marion, Vollmer, Jörg

Journal:

Journal of Interferon & Cytokine Research

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

9

CPG ODN allows lower dose of antigen against hepatitis B surface antigen in BALB/c mice

Weeratna, Risini, Comanita, Lacrimioara, Davis, Heather L

Journal:

Immunology & Cell Biology

Year:

2003

Language:

english

File:

PDF, 244 KB

english, 2003

10

CpG ODN can re-direct the Th bias of established Th2 immune responses in adult and young mice

Risini D Weeratna, Cynthia L Brazolot Millan, Michael J McCluskie, Heather L Davis

Journal:

FEMS Immunology & Medical Microbiology

Year:

2001

Language:

english

File:

PDF, 286 KB

english, 2001

11

Parenteral and mucosal prime-boost immunization strategies in mice with hepatitis B surface antigen and CpG DNA

Michael J McCluskie, Risini D Weeratna, Paul J Payette, Heather L Davis

Journal:

FEMS Immunology & Medical Microbiology

Year:

2002

Language:

english

File:

PDF, 608 KB

english, 2002

12

CpG DNA induces stronger immune responses with less toxicity than other adjuvants

Risini D Weeratna, Michael J McCluskie, Yu Xu, Heather L Davis

Journal:

Year:

2000

Language:

english

File:

PDF, 417 KB

english, 2000

13

Comparison of D-G3139 and Its Enantiomer L-G3139 in Melanoma Cells Demonstrates Minimal In Vitro but Dramatic In Vivo Chiral Dependency

Lai, Johnathan C, Brown, Bob D, Voskresenskiy, Anatoliy M, Vonhoff, Stefan, Klussman, Sven, Tan, Wenzhi, Colombini, Marco, Weeratna, Risini, Miller, Paul, Benimetskaya, Luba, Stein, Cy A

Journal:

Molecular Therapy

Year:

2007

Language:

english

File:

PDF, 313 KB

english, 2007

14

Evaluation of recombinant adenovirus vectors and adjuvanted protein as a heterologous prime-boost strategy using HER2 as a model antigen

Haq, Kamran, Jia, Yimei, Elahi, S. Mehdy, MacLean, Susanne, Akache, Bassel, Gurnani, Komal, Chattopadhyay, Anindita, Nazemi-Moghaddam, Nazila, Gilbert, Rénald, McCluskie, Michael J., Weeratna, Risini

Journal:

Year:

2019

Language:

english

File:

PDF, 1.55 MB

english, 2019

15

Treatment of intravaginal HSV-2 infection in mice: A comparison of CpG oligodeoxynucleotides and resiquimod (R-848)

Michael J. McCluskie, Janna L.M. Cartier, Amy J. Patrick, Dusan Sajic, Risini D. Weeratna, Kenneth L. Rosenthal, Heather L. Davis

Journal:

Antiviral Research

Year:

2006

Language:

english

File:

PDF, 459 KB

english, 2006

16

Priming of immune responses to hepatitis B surface antigen in young mice immunized in the presence of maternally derived antibodies

Risini D Weeratna, Cynthia L Brazolot Millan, Michael J McCluskie, Claire-Anne Siegrist, Heather L Davis

Journal:

FEMS Immunology & Medical Microbiology

Year:

2001

Language:

english

File:

PDF, 476 KB

english, 2001

17

Potential use of CpG ODN for cancer immunotherapy

Risini D. Weeratna, Heather L. Davis, Liana Medynski, Arthur M. Krieg

Journal:

Update on Cancer Therapeutics

Year:

2006

Language:

english

File:

PDF, 344 KB

english, 2006

18

The potential of oligodeoxynucleotides as mucosal and parenteral adjuvants

Michael J. McCluskie, Risini D. Weeratna, Heather L. Davis

Journal:

Year:

2001

Language:

english

File:

PDF, 112 KB

english, 2001

19

Mucosal immunization of mice using CpG DNA and/or mutants of the heat-labile enterotoxin of Escherichia coli as adjuvants

Michael J McCluskie, Risini D Weeratna, John D Clements, Heather L Davis

Journal:

Year:

2001

Language:

english

File:

PDF, 374 KB

english, 2001

20

Immunogenicity of a peptide-based anti-IgE conjugate vaccine in non-human primates

Weeratna, Risini D., Chikh, Ghania, Zhang, Lu, Fraser, James D., Thorn, Jennifer M., Merson, James R., McCluskie, Michael J., Champion, Brian R., Davis, Heather L.

Journal:

Immunity, Inflammation and Disease

Year:

2016

Language:

english

File:

PDF, 989 KB

english, 2016

21

CpG DNA can Induce Strong Th1 Humoral and Cell-Mediated Immune Responses against Hepatitis B Surface Antigen in Young Mice

Cynthia L. Brazolot Millan, Risini Weeratna, Arthur M. Krieg, Claire-Anne Siegrist and Heather L. Davis

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.51 MB

english, 1998

22

The Potential of CpG Oligodeoxynucleotides as Mucosal Adjuvants

Weeratna, Risini D., Payette, Paul J., Davis, Heather L.

Journal:

Critical Reviews™ in Immunology

Year:

2001

Language:

english

File:

PDF, 204 KB

english, 2001

23

Paclitaxel reduces regulatory T cell numbers and inhibitory function and enhances the anti-tumor effects of the TLR9 agonist PF-3512676 in the mouse

Alain P. Vicari, Rachel Luu, Ningli Zhang, Shobhna Patel, Shawn R. Makinen, Douglas C. Hanson, Risini D. Weeratna, Arthur M. Krieg

Journal:

Cancer Immunology, Immunotherapy

Year:

2009

Language:

english

File:

PDF, 628 KB

english, 2009

24

Testing of CpG-Optimized Protein and DNA Vaccines against the Hepatitis B Virus in Chimpanzees for Immunogenicity and Protection from Challenge

Payette, Paul J., Ma, Xiaoying, Weeratna, Risini D., McCluskie, Michael J., Shapiro, Max, Engle, Ron E., Davis, Heather L., Purcell, Robert H.

Journal:

Year:

2006

Language:

english

File:

PDF, 270 KB

english, 2006

25

The role of CpG in DNA vaccines

Michael J. McCluskie, Risini D. Weeratna, Heather L. Davis

Journal:

Seminars in Immunopathology

Year:

2000

Language:

english

File:

PDF, 539 KB

english, 2000

26

CpG DNA is an effective oral adjuvant to protein antigens in mice

Michael J McCluskie, Risini D Weeratna, Arthur M Krieg, Heather L Davis

Journal:

Year:

2000

Language:

english

File:

PDF, 218 KB

english, 2000

27

Current opportunities and challenges in intradermal vaccination

Chen, David, Bowersock, Terry, Weeratna, Risini, Yeoh, Thean

Journal:

Therapeutic Delivery

Year:

2015

Language:

english

File:

PDF, 808 KB

english, 2015

28

Reduction of Antigen Expression from DNA Vaccines by Coadministered Oligodeoxynucleotides

WEERATNA, RISINI, MILLAN, CYNTHIA L. BRAZOLOT, KRIEG, ARTHUR M., DAVIS, HEATHER L.

Journal:

Antisense and Nucleic Acid Drug Development

Year:

1998

Language:

english

File:

PDF, 3.53 MB

english, 1998

29

Optimization Strategies for DNA Vaccines

Weeratna, Risini D., McCluskie, Michael J., Comanita, Lacrimiora, Wu, Tong, Davis, Heather L.

Journal:

Year:

2000

Language:

english

File:

PDF, 282 KB

english, 2000

30

Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation

Jörg Vollmer, Risini D. Weeratna, Marion Jurk, Ulrike Samulowitz, Michael J. Mccluskie, Paul Payette, Heather L. Davis, Christian Schetter, Arthur M. Krieg

Journal:

Year:

2004

Language:

english

File:

PDF, 328 KB

english, 2004

31

Comparison of D-G3139 and Its Enantiomer L-G3139 in Melanoma Cells Demonstrates Minimal In Vitro but Dramatic In Vivo Chiral Dependency

Lai, Johnathan C, Brown, Bob D, Voskresenskiy, Anatoliy M, Vonhoff, Stefan, Klussman, Sven, Tan, Wenzhi, Colombini, Marco, Weeratna, Risini, Miller, Paul, Benimetskaya, Luba, Stein, Cy A

Journal:

Molecular Therapy

Year:

2007

File:

PDF, 313 KB

2007

32

Priming of immune responses to hepatitis B surface antigen in young mice immunized in the presence of maternally derived antibodies

Risini D Weeratna, Cynthia L Brazolot Millan, Michael J McCluskie, Claire-Anne Siegrist, Heather L Davis

Journal:

FEMS Immunology & Medical Microbiology

Year:

2001

Language:

english

File:

PDF, 474 KB

english, 2001

33

CpG ODN can re-direct the Th bias of established Th2 immune responses in adult and young mice

Risini D Weeratna, Cynthia L Brazolot Millan, Michael J McCluskie, Heather L Davis

Journal:

FEMS Immunology & Medical Microbiology

Year:

2001

Language:

english

File:

PDF, 289 KB

english, 2001

34

In vivo screen of genetically conserved Streptococcus pneumoniae proteins for protective immunogenicity

Anderson, Richard J., Guru, Siradanahalli, Weeratna, Risini, Makinen, Shawn, Falconer, Derek J., Sheppard, Neil C., Lang, Susanne, Chang, Bingsheng, Goenaga, Anne-Laure, Green, Bruce A., Merson, James

Journal:

Year:

2016

Language:

english

File:

PDF, 1.75 MB

english, 2016

35

Parenteral and mucosal prime-boost immunization strategies in mice with hepatitis B surface antigen and CpG DNA

Michael J McCluskie, Risini D Weeratna, Paul J Payette, Heather L Davis

Journal:

FEMS Immunology & Medical Microbiology

Year:

2002

Language:

english

File:

PDF, 605 KB

english, 2002

36

CpG ODN and ISCOMATRIX Adjuvant: A Synergistic Adjuvant Combination Inducing Strong T-Cell IFN- Responses

McCluskie, Michael J., Weeratna, Risini D., Evans, Dana M., Makinen, Shawn, Drane, Debbie, Davis, Heather L.

Journal:

BioMed Research International

Year:

2013

Language:

english

File:

PDF, 730 KB

english, 2013

37

Effects of KLK Peptide on Adjuvanticity of Different ODN Sequences

Chikh, Ghania, Luu, Rachel, Patel, Shobhna, Davis, Heather, Weeratna, Risini

Journal:

Year:

2016

Language:

english

File:

PDF, 1.51 MB

english, 2016

38

A Novel Class of Immune-Stimulatory CpG Oligodeoxynucleotides Unifies High Potency in Type I Interferon Induction with Preferred Structural Properties

Samulowitz, Ulrike, Weber, Markus, Weeratna, Risini, Uhlmann, Eugen, Noll, Bernhard, Krieg, Arthur M., Vollmer, Jörg

Journal:

Oligonucleotides

Year:

2010

Language:

english

File:

PDF, 1.73 MB

english, 2010

39

Pitfalls of vaccinations with WT1-, Proteinase3- and MUC1-derived peptides in combination with MontanideISA51 and CpG7909

Jürgen Kuball, Karin de Boer, Eva Wagner, Mohammed Wattad, Edite Antunes, Risini D. Weeratna, Alain P. Vicari, Carina Lotz, Suzanne van Dorp, Samantha Hol, Philip D. Greenberg, Wolfgang Heit, Heather

Journal:

Cancer Immunology, Immunotherapy

Year:

2011

Language:

english

File:

PDF, 392 KB

english, 2011

40

TLR agonists as vaccine adjuvants: comparison of CpG ODN and Resiquimod (R-848)

Risini D. Weeratna, Shawn R. Makinen, Michael J. McCluskie, Heather L. Davis

Journal:

Year:

2005

Language:

english

File:

PDF, 327 KB

english, 2005

41

Novel Adjuvant Systems

McCluskie, Michael, Weeratna, Risini

Journal:

Current Drug Targets - Infectious Disorders

Year:

2001

Language:

english

File:

PDF, 57 KB

english, 2001

42

Evaluation of recombinant adenovirus vectors and adjuvanted protein as a heterologous prime-boost strategy using HER2 as a model antigen

Haq, Kamran, Jia, Yimei, Elahi, S. Mehdy, MacLean, Susanne, Akache, Bassel, Gurnani, Komal, Chattopadhyay, Anindita, Nazemi-Moghaddam, Nazila, Gilbert, Rénald, McCluskie, Michael J., Weeratna, Risini

Journal:

Year:

2019

File:

PDF, 1.55 MB

2019

43

CpG DNA overcomes hyporesponsiveness to hepatitis B vaccine in orangutans

Heather L. Davis, Irma Suparto, Risini Weeratna, Jumintarto, Diah Iskandriati, Siti Chamzah, Amir Ma’ruf, Citrakasih Nente, Dyah Pawitri, Arthur M. Krieg, Heriyanto, Willie Smits, Dondin Sajuthi

Journal:

Year:

2000

Language:

english

File:

PDF, 152 KB

english, 2000

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